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Vita C Forte
Announcing
Vita C Forte, a new 10% Vitamin C Serum with 2.5% hyaluronic acid and
Erythorbic Acid. Both Vitamin C and hyaluronic acid appear to be two of
the prime components in the anti-aging battle.
In the past year, several
products containing Vitamin C has appeared on the market. The results
have been very impressive and have received coverage in Vogue, Harper's
Bazaar, Marie Claire(U.K.), Cosmoplitan, Allure, Health and many other
publications.
Vitamin C is now known as a
major component in the production of collagen fibers, which are
necessary for firm, youthful appearing skin.[1,2,3] Recent research has
led to a stabilized Vitamin C that penetrates to the deep layers of the
skin.
Recent studies conducted by
Darr et al provides evidence that vitamin C levels of the skin can be
severely depleted, especially after UV irradiation. Topical use of
vitamin C (l-ascorbic acid) shows promise as a broad-spectrum
photoprotectant, functioning as biological co-factor and antioxidant.[4]
A very interesting article by Ghersetich et al on hyaluronic acid in
cutaneous aging was recently published. We have been taught to believe
that wrinkles occur and the skin sags on aging because of cross-linking
of elastin and collagen due to the presence of free radicals, part of
which is due to excessive exposure to UV radiation. Ghersetich proposes
that these phenomena may actually be due to a decrease or alteration in
hyaluronic acid in the dermis. In elderly individuals, all components of
the skin and subcutaneous tissue undergo histologic and ultrastructural
changes. Turgidity of the dermis appears decreased, presumably due to
altered patterns and levels of glycosaminoglycans (GAGs), especially
hyaluronic acid and dermatin sulfate, the most common. A linear,
age-related decrease in the content of GAGs (mainly hyaluronic acid) is
now hypothesized in aged human skin.[4]
There are many other
research papers that can be cited, but the above brief excerps should
point out the benefits of Vitamin C and hyaluronic acid to the skin.
References
1. Phillips CL; Tajima S;
Pinnell SR. Ascorbic acid and transforming growth factor-beta 1 increas
collagen biosynthesis via different mechanisms: coordinate regulation of
pro alpha 1(I) and Pro alpha 1(III) collagens. Department of Medicine,
Duke University Medical Center, Durham, NC 27710. Arch Biochem Biophys
295: 397-403 (1992)
2. Houglym KP; Brenner DA; Chojkier M. Ascorbic acid stimulation of
collagen biosynthesis independent of hydroxylation. Department of
Medicine, Veterans Affairs Medical Center, San Diego, CA. Am J Clin Nutr
54: 1141S-1143S (1991)
3. Middelkoop E; de Vries HJ;
Ruuls L; Everts V; Wildevuur CH; Westerhof W. Adherence, proliferation
and collagen turnover by human fiberblasts seeded into different types
of collagen sponges. Department of Cell Biology and Histology, Academic
Medical Center, Amsterdam, The Netherlands. Cell Tissue Res 280: 447-53
(1995)
4. Fox, Charles. Topical
bioactive materials. (part 2). Cosmetics and Toiletries, Sept 1994 v109
n9 p83(22)
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